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A ganglion cyst, also known as a bible cyst, is a swelling that often appears on or around joints and tendons in the hand or foot. The size of the ganglion or cyst can vary over time. It is most frequently located around the dorsum of the wrist and on the fingers. The term "Bible bump" comes from a common treatment in the past that consisted of hitting the cyst with a Bible or another large book.[1] Rupture of the cyst is rarely curative; trying to pop it typically does not fix it but in fact worsens it.
Ganglion cysts are idiopathic, but presumably reflect a variation in normal joint or tendon sheath function. Cysts near joints are connected to the joint and the leading theory is that a type of check valve forms that allows fluid out of the joint, but not back in. The cyst contains clear fluid similar to, but thicker than, normal synovial fluid. They are most often found around the wrist joint, especially at the scapho-lunate joint, which accounts for 80% of all ganglion cysts.

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